Coordinating European Cell-based Tolerance-inducing Therapies efforts

Minimises overlap and maximises comparison of the diverse approaches

Establishing consensus on monitoring parameters

Join A FACTT to focus and accelerate the CTT field

A FACTT: progress in an efficient, safe and cost-effective way

A FACTT is pushing the limits, inviting you to come along and join us !

The number of patients with autoimmune diseases and recipients of organ or stem-cell transplants is increasing worldwide. Currently, these patients require lifelong administration of immunosuppressive drugs. Often, these drugs are ineffective, expensive and show severe side-effects. More effective and safer therapies aimed at modifying unwanted immune responses permanently or for prolonged periods are needed.

Accumulating knowledge on mechanisms of immune tolerance has led to development of specific Cell-based Tolerance-inducing Therapies (CTT) with the specific objectives to restrain unwanted immune reactions long-term. For patients, personalised CTT will represent a breakthrough for healthcare and quality of life.

Clinical CTT studies are underway or starting in single European institutes. The used CTT products are diverse and the efficacy of therapy is monitored by different parameters. This creates the risk of redundancy in trials and suboptimal performance indicators for comparison of trial outcomes.

The main objective of A FACTT is to initiate a network that will coordinate European CTT efforts to minimise overlap and maximise comparison of the diverse approaches through establishment of consensus monitoring parameters. The A FACTT-Action will thus focus and accelerate the CTT field and ensure that the field will progress in an efficient, safe and cost-effective way.

The A FACTT Project

The A FACTT Project
Do you like to quickly learn more about the A FACTT project ? Please click here and find all information about the project, its objectives, its background and the benefits, as well as your starting point to the scientific work being carried out.

How to join A FACTT

How to join A FACTT
Are you interested in the A FACTT project and would you like to join us and become part of Europe's biggest network on Cell-based Tolerance-inducing Therapies ? Please apply here !

Contact A FACTT

Contact A FACTT
The A FACTT project is to focus and accelerate the CTT field. Should you like to receive more information about the project, please find here the information how to contact us.

Join A FACTT today
and help focusing the CTT field !

Design mod for A FACTT by IDYMA.