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Final AFACTT Conference Barcelona 9 -11 October 2017

09/10/2017 - 11/10/2017

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PLEASE USE THIS LINK TO DOWNLOAD AND PRINT YOUR PERSONAL COPY OF THE PROGRAM

PLEASE NOTE THAT THE CONFERENCE WILL TAKE PLACE IN TWO DIFFERENT VENUES:

(1) Monday 9 and Wednesday 11 in Barcelona city (Institut Català de la Salut, Gran Via de Corts Catalanes, 587).

(2) Tuesday 10 in Badalona (Fundació Institut d’investigació Germans Trias i Pujol,  Carretera Can Ruti, Cami Escoles s/n).

A special bus shuttle service will be established from Barcelona city to Badalona venue


PROGRAM

 

Monday, 9th October – Location ICS GRAN VIA DE CORTS CATALANES – BARCELONA

 

OPENING

10.30 – 11.00 Registration

11.00 – 11.15 Welcome
Eva Martínez Cáceres (ES)

11.15 – 11.45 Opening conference:
Tolerance – Robert Lechler (UK)

11.45- 15.05 SESSION – Tregs WITH LUNCH BREAK
Chair: Li Zhou (TxCell) and Piotr Trzonkowski (PL)

11.45-12-10 From polyTreg to CARTreg – Giovanna Lombardi (UK)
12.10-12.20 CARTreg – Li Zhou (Txcell)
12.20-12.45 Optimising Treg therapy in transplantation – lessons from preclinical models – Joanna Hester (UK)

12.45-13.30 LUNCH

13:30 – 15.05
13.30-14.15 CD4+ Treg in transplantation, lesson from the clinic – Qizhi Tang (USA)
14.15-14.40 Progress in the clinical application of CD4+ T regulatory cells in autoimmunity –   Natalia Marek-Trzonkowska (POL)
14.40-15.05 CD8+ Treg new players in allograft tolerance – Ignacio Anegon (FR)

15.05 – 15.35 COFFEE TEA BREAK

15:35 – 17.30 SESSIONS – Tregs (2)
Chair: Giovanna Lombardi and Irma Joosten

15.35-16.00 Innate immune training as a means of generating myeloid regulatory cells that control autoimmunity – Kingston Mills (IR)
16.00-16.25 Low-dose IL-2 therapy for Treg expansion and tolerance – Marc Martinez Llordella (UK)
16.25-17.30 Roundtable on Treg

17.30 – 18.30 FINAL BM1305 MANAGEMENT COMMITTEE MEETING

20.00 NETWORKING DINNER


 

Tuesday, 10th October – Location 2 BADALONA

 

NOTE: BUS SHUTTLE FROM ICS VENUE (GRAN VIA DE CORTS CATALANES) TO BADALONA VENUE
Departure from ICS VENUE: 08.00-08.15

9.15 – 9.30 Welcome
Manel Puig Domingo, Director IGTP

MORNING SESSION 09.30-11.15
09.30-09.55 Tolerogenic dendritic cells in autoimmunity, where do we go? – CH Hilkens (UK)
09.55-10.25 Auto-antigenic protein-derived peptides bound to HLA-DRB1 molecules as candidates for dendritic cells loading in rheumatoid arthritis.
JC Aguillon (CHILE)
10.25-10.50 Tolerogenic dendritic cells in MS – Nathalie Cools/ E. Martínez Cáceres (BE)(ES)
10.50-11.15 Tolerogenic Dendritic Cells in Type 1 Diabetes Patients – Lenka Palová-Jelínková / David Funda Prague, (CZ)

11.15-11.45 COFFEE BREAK

11.45 – 13.30 SESSION: Cell based tolerance inducing therapies in transplantation
Chair: Nathalie Cools and and James Hutchinson

11.45-12.10 Cellular therapy in organ transplantation: Go for tolerance or minimization first? – Ed Geissler (GER)
12.10-12.35 Autologous tolerogenic dendritic cells therapy in human transplantation – Maria Cristina Cuturi (FR)
12.35-13.00 IL-10-producing tolerogenic dendritic cells for induction of allo-specific tolerance – Silvia Gregori (IT)

13.30-14.45 LUNCH BREAK & POSTER SESSION
ABSTRACT PRESENTATIONS
Chair: Joana Miranda and Eva Martinez-Caceres

14.45-14.55 PUTRID: a marker that identifies pure and stable regulatory T cells – Rianne Opstelten (NL)
14.55-15.05 The immunogenicity of allogeneic cells for adoptive cellular therapy can be overcome by co-administration of sub-therapeutic immunosuppression – Kate Milward (UK)
15.05-15.15 Tolerogenic immunotherapy with peptide-pulsed dendritic cells in rheumatoid arthritis – Rachel Spiering (UK)
15.15.15.25 Delaying the autoimmune attack in a rodent model of type-1 diabetes.- Christian Lachaud /Bernat Soria (ES)
15.25.15.35 Towards Treg application in clinics – University of Chicago experience – Karolina Golab ( USA)

15.35- 17.45 SESSION: Immune monitoring
Chair: Thomas Giese and Marieke van Ham

15.35-16.00 Immune monitoring – how much standardization is possible and what can we learn from our mistakes – Birgit Sawitzki (GER)
16.00-16.25 Coffee break
16.25-16.50 Immunomonitoring of tolerogenic Treg-directed therapies Nathali Grageda (UK)
16.50-17.15 In vivo imaging of live cell therapies. Gilbert Fruhwirth (UK)
17.15-17.45 Roundtable

17.45 – 18.15 CLOSING OF COST ACTION BM1305- Future plans.
Anja ten Brinke (NL) and Eva Martínez Cáceres (ES)

20.00
DINNER

BUS to restaurant from Badalona venue departs around 18.45-19.00
BUS to barcelona from restaurant departs around 22.30-23.00

 

Wednesday, 11th October – Location ICS – GRAN VIA DE CORTS CATALANES – BARCELONA

Joint meeting COST ACTIONS: A FACTT & Mye-EUNITER

9.15 – 9.30 Welcome
Eva Martínez Cáceres Chair BM1305 (ES)
Sven Brandau, Chair BM1404 (GER)

9.30-10.45 SESSION: Yin and Yan of suppressor cells – induction of tolerance by cell-based approaches vs break tolerance in cancer and infections
09.30-09.55 Myeloid regulatory cell biology – Vincenzo Bronte (IT) (BM1404)
09.55-10.20 Characterization of human tolerogenic dendritic cells used in clinical trial Aurelie Moreau (FR) (BM1305)
10.20-10.45 Roundtable

10.45-11.15 COFFEE BREAK

11.15-13.00 SESSION: Functional monitoring of regulatory cells
11.15-11.40 Antigen-specific T cell responses – Anja ten Brinke (NL) (BM1305)
11.40-12.05 MyeFun assay:  towards a standardized assay to assess suppressive activity of MDSC on T cells? – Annika Bruger (BE) (BM1404)
12.05-12.30 Metabolic regulation of regulatory T cell trafficking Federica Marelli-Berg (UK)
12.30-13.00 Roundtable

13.00 -14.00 LUNCH

14.00-16.40 SESSION: Effect of the microenvironment on suppressive cells
14.00-14.25 Functionally distinct dendritic cell subsets in the tumor microenvironment- Jo Van Ginderachter (BE) (BM1404)
14.25-14.50 Immunosuppression induced by chronic inflammation and MDSC in melanoma microenvironment and its overcoming – Viktor Umasky (GER) (BM1404)
14.40-15.15 Epigenetic modulation of myeloid cells as a primer for tolerance induction – Bernard Vanhove (FR) (BM1404)

15.15-15.45 COFFEE TEA BREAK

15.45-16.10 Metabolic regulation of myeloid suppressor functions – Antonio Sica (IT)
16.10-16.40 Roundtable

16.45 – 17.15 DISCUSSION and concluding remarks

Details

Start:
09/10/2017
End:
11/10/2017
Website:
http://www.afactt.eu

Venue

Institut Català de la Salut
Gran Via de les Corts Catalanes, 587
Barcelona, ONLY MONDAY AND WEDNESDAY; TUESDAY BADALONA VENUE 08007 Spain
Phone:
93 482 44 42

Organizer

Health Sciences Research Institute of the Germans Trias i Pujol Foundation
Website:
www.afactt.eu